Hydroxydiosmin (Hidrosmin) is a derivative of Diosmin, which belongs to a group of semi-synthetic flavonoids with stronger pharmacological activity and better water solubility. The following is a detailed description of Hydroxydiosmin:<\/p>\n\n\n\n
1. Basic Information<\/p>\n\n\n\n
Chemical name: 5-O-(\u03b2-Hydroxyethyl)diosmin (5-O-(\u03b2-Hydroxyethyl)diosmin)<\/p>\n\n\n\n
CAS No.: 115960-14-0<\/p>\n\n\n\n
Molecular Formula: C\u2083\u2080H\u2083\u2086O\u2081\u2086<\/p>\n\n\n\n
Molecular weight: 652.597<\/p>\n\n\n\n
Properties: yellow to yellow-brown powder<\/p>\n\n\n\n
Specification: Common specification is 85% HPLC (High Performance Liquid Chromatography) purity, there are also 98% HPLC purity products.<\/p>\n\n\n\n
2. Pharmacological effects<\/p>\n\n\n\n
Enhancement of venous tone:<\/p>\n\n\n\n
Hydroxydiosmin enhances venous elasticity and reduces venous dilatation and stasis by prolonging the contractile effect of adrenaline on the venous wall.<\/p>\n\n\n\n
Improve venous return, reduce lower limb edema and pain.<\/p>\n\n\n\n
Improves microcirculation:<\/p>\n\n\n\n
Reduce capillary permeability, enhance capillary resistance, and promote tissue fluid return.<\/p>\n\n\n\n
Regulate microvascular function, improve blood supply and nutritional metabolism of local tissues.<\/p>\n\n\n\n
Promote lymphatic return:<\/p>\n\n\n\n
Increase the contraction frequency and drainage speed of lymphatic vessels, reduce tissue edema.<\/p>\n\n\n\n
It has a significant alleviating effect on lymphedema.<\/p>\n\n\n\n
Anti-inflammatory effect:<\/p>\n\n\n\n
Inhibit the generation and release of inflammatory mediators, reduce inflammatory response.<\/p>\n\n\n\n
It has therapeutic effect on inflammation caused by chronic venous insufficiency.<\/p>\n\n\n\n
3. Clinical application<\/p>\n\n\n\n
Venous diseases:<\/p>\n\n\n\n
Chronic venous insufficiency: relieve leg heaviness, pain, morning soreness, edema and other symptoms.<\/p>\n\n\n\n
Varicose veins: reduce swelling and discomfort caused by varicose veins in lower limbs.<\/p>\n\n\n\n
Deep vein thrombosis syndrome: to assist in the treatment of venous dysfunction following deep vein thrombosis.<\/p>\n\n\n\n
Lymphatic disorders:<\/p>\n\n\n\n
Lymphedema: promotes the return of lymphatic fluid and reduces swelling of the limbs.<\/p>\n\n\n\n
Hemorrhoids:<\/p>\n\n\n\n
Acute flare-ups: relieve anal moisture, itching, blood in stool, pain and other symptoms caused by hemorrhoidal varicose veins.<\/p>\n\n\n\n
4. Advantages<\/p>\n\n\n\n
Better water solubility: Hydroxydiosmin has better water solubility than Diosmin, which is easier to be absorbed by the body and requires less dosage when taking.<\/p>\n\n\n\n
Stronger therapeutic effect: Hydroxydiosmin shows stronger therapeutic effect in the treatment of edema and varicose vein ulcers.<\/p>\n\n\n\n
High safety: As a semi-synthetic drug, hydroxydiosmin has shown good safety and tolerability in clinical application.<\/p>\n","protected":false},"excerpt":{"rendered":"
Hydroxydiosmin (Hidrosmin) is a derivative of Diosmin, […]<\/p>\n","protected":false},"author":3,"featured_media":1834,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1833","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news"],"_links":{"self":[{"href":"https:\/\/hidrosmin.com\/index.php?rest_route=\/wp\/v2\/posts\/1833","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hidrosmin.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hidrosmin.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hidrosmin.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/hidrosmin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1833"}],"version-history":[{"count":1,"href":"https:\/\/hidrosmin.com\/index.php?rest_route=\/wp\/v2\/posts\/1833\/revisions"}],"predecessor-version":[{"id":1835,"href":"https:\/\/hidrosmin.com\/index.php?rest_route=\/wp\/v2\/posts\/1833\/revisions\/1835"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/hidrosmin.com\/index.php?rest_route=\/wp\/v2\/media\/1834"}],"wp:attachment":[{"href":"https:\/\/hidrosmin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1833"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hidrosmin.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1833"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hidrosmin.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1833"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}