Troxerutin is an organic compound that is described in detail below:
1. Basic Information
Chemical name: Troxerutin, also known as Troxerutin, Vitamin P4. Hydroxyethyl Rutin, etc.
Chemical formula: C33H42O19
Molecular weight: 742.675
CAS No.: 7085-55-4
Appearance: light yellow powder
2. Harmacological effects
Troxerutin is a semi-synthetic flavonoid compound made from rutin by hydroxyethylation, which has a variety of pharmacological effects:
Inhibit platelet and red blood cell coagulation: Troxerutin can inhibit platelet and red blood cell coagulation, thus preventing the formation of thrombus.
Improvement of microcirculation: Troxerutin can increase the oxygen content in the blood, improve microcirculation, and promote neoangiogenesis to enhance collateral circulation.
Protecting endothelial cells: Triclopidine has a protective effect on endothelial cells, and can counteract vascular damage caused by 5-hydroxytryptamine and bradykinin.
Increase capillary resistance: Troxerutin can reduce capillary permeability, increase capillary resistance and prevent edema caused by elevated vascular permeability.
In addition, Troxerutin also has the effects of anti-radiation damage, anti-inflammation, anti-allergy, anti-ulcer and so on.
3. Indications
Troxerutin is mainly used to treat a variety of vascular diseases, including but not limited to:
Cerebral thrombosis and hemiparesis and aphasia due to cerebral embolism.
Pre-myocardial infarction syndrome, arteriosclerosis.
Central retinitis, thrombophlebitis, varicose veins.
Edema due to elevated vascular permeability, etc.