Hydroxydiosmin (Hidrosmin) is a semi-synthetic flavonoid with a wide range of pharmacological effects and is widely used in medicine. The following is a detailed analysis of its main effects:
1. Vasoprotection and capillary stabilization
Mechanism of action: Hydroxydiosmin can reduce venodilatation and venous stasis, improve microcirculation, and at the same time enhance the stability of capillaries and reduce their permeability.
Clinical Significance:
Veno-lymphatic insufficiency: relieves heavy legs, pain, soreness and edema, enhances venous tone, promotes venous return and reduces blood stagnation.
Diabetic complications: improve microangiopathy and retinopathy, maintain normal blood perfusion of tissues and organs.
2. Anti-inflammatory and antioxidant
Mechanism of action: inhibit the production of inflammatory factors (e.g. TNF-α, IL-6) to reduce the inflammatory response; at the same time, scavenging free radicals to protect blood vessels from oxidative stress damage.
Clinical significance:
Anti-inflammatory effect: helps to relieve various symptoms caused by inflammation, such as redness, swelling and pain.
Antioxidant effect: fight against oxidative stress, slow down cell aging, and protect the health of blood vessels.
3. Promote lymphatic return
Mechanism of action: Enhance the contraction ability of lymphatic vessels, improve the function of lymphatic system.
Clinical significance:
Lymphedema treatment: assist to reduce limb swelling, improve tissue nutrition supply and metabolic waste discharge.
4. Other effects
Improvement of hemorrhoid symptoms: reduce anal pain, blood in stool, swelling, itching, etc., improve local blood circulation, relieve congestion and edema.
Good pharmacokinetic properties: Compared with Diosmin, HydroxyDiosmin has better water solubility and bioavailability, lower dosage and easier to be absorbed by the body.