Diosmin has a variety of potential applications, mainly in anti-inflammatory, improve microcirculation, anti-tumor and other aspects, as follows:
1. Anti-inflammatory treatment
Digestive system diseases: Diosmin can reduce the inflammation of the digestive system, such as gastritis and enteritis. In addition, it can inhibit the growth of Helicobacter pylori, thus reducing gastritis caused by Helicobacter pylori infection.
Respiratory system diseases: Diosmin can reduce inflammation of the respiratory system, such as bronchitis, pneumonia and so on. At the same time, it can also inhibit the replication of viruses, thus reducing respiratory diseases caused by viral infections.
Arthritis: Diosmin can reduce the symptoms of arthritis, such as pain and swelling. In addition, it can inhibit the destruction of joint cartilage, thus slowing down the progress of arthritis.
Skin diseases: Diosmin is able to reduce skin inflammation, such as dermatitis and eczema. In addition, it can inhibit the proliferation of skin cells, thus reducing the symptoms of skin diseases.
Other diseases: Diosmin can also be applied to the treatment of other inflammation-related diseases, such as cardiovascular disease, diabetes, etc.
2. Improvement of microcirculation disorders
Venous diseases: Diosmin is commonly used in the treatment of varicose veins, deep vein thrombosis and other venous diseases. It can effectively improve venous return, reduce lower limb edema and pain, and improve patients’ quality of life.
Hemorrhoid treatment: Hemorrhoid patients are often accompanied by edema and pain around the anus, Diosmin can reduce edema around the anus by improving microcirculation and relieve the discomfort caused by hemorrhoids.
Other microcirculation disorders: For various symptoms caused by microcirculation disorders, such as diabetic retinopathy, diabetic neuropathy, etc., Diosmin is able to improve the stability of capillaries and reduce the permeability of capillaries, so as to relieve the symptoms.
3. Anti-tumor effect
Inhibit the proliferation of tumor cells: Diosmin has anti-tumor activity and can inhibit the growth and proliferation of tumor cells. Experiments show that Diosmin has significant inhibitory effect on human gastric cancer cells SGC-7901. colon cancer cells LoVo and human breast cancer cells MCF-7 and other tumor cells.
Induction of apoptosis: Diosmin can also induce apoptosis of tumor cells and reduce the expression of cell cycle proteins D1 and E, thus inhibiting the growth of tumor cells.
4. Other potential applications
Anti-neurodegenerative diseases: Diosmin has anti-neurodegenerative disease activity and can improve nerve function. It is found that Diosmin can reduce the content of β-amyloid (Aβ) in the brain of mice with Alzheimer’s disease, inhibit the deposition of Aβ, and improve the memory function of mice, improve learning and memory ability.
Protection of cardiovascular system: Diosmin has a protective effect on the cardiovascular system, which can reduce blood pressure and improve myocardial function. Research shows that Diosmin can reduce blood pressure in rats with renal hypertension, and improve cardiomyocyte damage and increase cardiomyocyte vitality.
Anti-motion sickness: Diosmin has anti-motion sickness activity, which can reduce motion sickness, seasickness and other symptoms. It has been shown that Diosmin can reduce the sensitivity of vestibular organs and alleviate the symptoms of motion sickness in rats.